Description
Parker’s PROPOR MR mycoplasma removal cartridge filter PROPOR MR
PROPOR MR mycoplasma removal filters are devices designed for the biopharmaceutical industry with a filtration value of 0.1 microns, which makes them effective in the fast and effective removal of mycoplasma.
It has a pre-filtration layer for higher flow capacity. This results in a faster process with a lower risk of contamination.
High flow options are available.
(PFAS-free models available)
Mycoplasma removal filter technical information
Filtration rating: 0.1 micron.
Length: 2.5 to 40 inches (65 to 1000 mm).
Seal material: Silicone, EPDM, Viton.
Filter construction: Pleated.
Grade: MURUS and DEMICAP capsules are available non-sterile or gamma irradiated.
Configuration of MURUS capsules: In-line and T-Port.
Compliance with specifications:
- Fully validated to ASTM F838-05 liquid bacterial test for liquids
- FDA 21 CFR part 177 compliant.
- USP Class VI plastics – 121°C.
Materials of manufacture:
- Filtration membrane: Polyethersulfone
- Membrane pre-filter: Polyethersulfone
- Upward support: Polyester
- Descending support: Polyester
Filter cartridges
- Inner support core: Polypropylene
- Outer protective cage: Polypropylene
- Plugs: Nylon
- Plug insert: 316L stainless steel
Syringe filters
- Body: Polypropylene
MURUS capsules
- Core: Polypropylene
- Cover: Polypropylene
- Plug insert: 316L Stainless Steel
- Capsule body: Polypropylene
- Capsule vent seals: Silicone
DEMICAP capsules
- Core: Polypropylene
- Cover: Polypropylene
- Plugs: Nylon
- Capsule body: Nylon
- Capsule vent seals: Silicone
- Filling bell: Polycarbonate
Operating temperature
Filter cartridges
Maximum continuous operating temperature 70°C (158°F)
Higher short-term temperatures during IPC:
- Up to 20°C (68°F) @ 5.0 barg (72.5 psig)
- Up to 40°C (104°F) @ 4.0 barg (58.0 psig)
- Up to 60°C (140°F) @ 3.0 barg (43.5 psig)
- Up to 80°C (176°F) @ 2.0 barg (29.0 psig)
- Up to 90°C (194°F) @ 1.7 barg (24.6 psig)
MURUS capsules
- Up to 25°C (77°F) @ 5.5 barg (79.7 psig)
- Up to 60°C (140°F) @ 2.8 barg (40.6 psig)
DEMICAP capsules
- Up to 40°C (104°F) at line pressures up to 5.0 barg (72.0 psig)
End cap configuration
Filter cartridges
- BF / 226 Bayonet
- End / 222
- Flat Top / 222
- Recess / 222
- BF / 222 Bayonet
Demi cartridge
- TRUSEAL
- 116
- Demi Stub
- Demi A B Std
Input connection size
MURUS capsules
- ¾” Tri-Clamp Clamp
- 1½” Tri-Clamp Clamp
- 1″ hose nozzle
- 1″ Tri-Clamp Clamp
- ½” hose nozzle
DEMICAP capsules
- 1″ Tri-Clamp Clamp
- ½” male NPT
- ½” hose nozzle,
- Stepped hose nozzle
- ¼” male NPT
- Walther QC
- Grommel / QC
Output connection size
MURUS capsules
- ¾” Tri-Clamp Clamp
- 1½” Tri-Clamp Clamp
- 1″ hose nozzle
- 1″ Tri-Clamp Clamp
- ½” hose nozzle
DEMICAP capsules
- 1″ Tri-Clamp Clamp
- ½” male NPT
- ½” hose nozzle
- Stepped hose nozzle
- ¼” male NPT
- Walther QC
- Grommel / QC
Retention of LRV > 10 of Acholeplasma laidlawii
The filter can reduce the concentration of Acholeplasma laidlawii by a factor of more than 10 orders of magnitude. (LVR > 10) So you have a high control of mycoplasma contamination.
Pre-filter layer to simplify processing
Including a pre-filtration layer protects the polyethersulfone (PES) layer and can condense the filtration train, resulting in less maintenance and cost savings.
Validated and tested filters.
Its suitability for biopharmaceutical applications has been validated by testing, as has its integrity in maintaining the sterility of the filtration process.
PROPOR MR filter applications for mycoplasma removal
PROPOR MR by 0.1 micron polyethersulfone (PES) media has been validated to meet the industry standard test for Brevundamonas diminuta and also with Acholeplasma laidlawii, a type of mycoplasma present in contaminated cell cultures.
