Description
The Parker PROPOR HC sterilizing filtration cartridge PROPOR HC
Parker’s PROPOR HC filters are designed for filtration of pharmaceutical and biological solutions with high capacity performance and capacity to ensure the sterilization process and prevent premature filter blockage.
PROPOR HC sterilizing filtration cartridges can handle large volumes of fluid with low levels of extractables.
The polyethersulfone (PES) membrane is highly chemically compatible and has the characteristic of low adhesion. This minimizes product loss due to the low adhesion of proteins and preservatives in the filtered liquids.
(PFAS-free models available)
Technical information of the sterilizing filter cartridge
Filtration rating: 0.2 microns.
Length: 2.5 to 40 inches (65 to 1000 mm).
Seal material: Silicone, EPDM, Viton.
Filter construction: Pleated.
Grade: MURUS and DEMICAP capsules are available non-sterile or gamma irradiated.
MURUS capsule configuration: In-line and T-Port.
Compliance with specifications:
- Fully validated according to ASTM F838-05 bacterial test for liquids.
- FDA 21 CFR part 177 compliant.
- USP Class VI plastics – 121°C.
Materials of manufacture:
- Filtration membrane: Polyethersulfone
- Membrane pre-filter: Polyethersulfone
- Upward support: Polyester
- Descending support: Polyester
Filter cartridges
- Inner support core: Polypropylene
- Outer protective cage: Polypropylene
- Plugs: Nylon
- Plug insert: 316L stainless steel
Syringe filters
- Body: Polypropylene
MURUS capsules
- Core: Polypropylene
- Cover: Polypropylene
- Plug insert: 316L Stainless Steel
- Capsule body: Polypropylene
- Capsule vent seals: Silicone
DEMICAP capsules
- Core: Polypropylene
- Cover: Polypropylene
- Plugs: Nylon
- Capsule body: Nylon
- Capsule vent seals: Silicone
- Filling bell: Polycarbonate
Operating temperature
Filter cartridges
Maximum continuous operating temperature 70°C (158°F)
Higher short-term temperatures during IPC:
- Up to 20°C (68°F) @ 5.0 barg (72.5 psig)
- Up to 40°C (104°F) @ 4.0 barg (58.0 psig)
- Up to 60°C (140°F) @ 3.0 barg (43.5 psig)
- Up to 80°C (176°F) @ 2.0 barg (29.0 psig)
- Up to 90°C (194°F) @ 1.7 barg (24.6 psig)
MURUS capsules
- Up to 25°C (77°F) @ 5.5 barg (79.7 psig)
- Up to 60°C (140°F) @ 2.8 barg (40.6 psig)
DEMICAP capsules
- Up to 40°C (104°F) at line pressures up to 5.0 barg (72.0 psig)
End cap configuration
Filter cartridges
- BF / 226 Bayonet
- End / 222
- Flat Top / 222
- Recess / 222
- BF / 222 Bayonet
Demi cartridge
- TRUSEAL
- 116
- Demi Stub
- Demi A B Std
Input connection size
MURUS capsules
- ¾” Tri-Clamp Clamp
- 1½” Tri-Clamp Clamp
- 1″ hose nozzle
- 1″ Tri-Clamp Clamp
- ½” hose nozzle
DEMICAP capsules
- 1″ Tri-Clamp Clamp
- ½” male NPT
- ½” hose nozzle,
- Stepped hose nozzle
- ¼” male NPT
- Walther QC
- Grommel / QC
Output connection size
MURUS capsules
- ¾” Tri-Clamp Clamp
- 1½” Tri-Clamp Clamp
- 1″ hose nozzle
- 1″ Tri-Clamp Clamp
- ½” hose nozzle
DEMICAP capsules
- 1″ Tri-Clamp Clamp
- ½” male NPT
- ½” hose nozzle
- Stepped hose nozzle
- ¼” male NPT
- Walther QC
- Grommel / QC
Superior performance compared to other options
Compared to conventional single-layer filter membranes, the optimized PES membrane can more effectively filter out impurities, enabling up to ten times higher performance.
Integrated pre-filtration layer
Thanks to the pre-filtration layer, filtration stages can be reduced, simplifying and condensing the process. This results in economic savings in maintenance costs and filtration consumables.
Sterilizing filtration of 0.2 microns
The 0.2 micron membrane is effective in retaining microorganisms, resulting in a sterile pharmaceutical product free of biological contaminants.
The membrane has been validated for sterility and integrity testing.
Sterilizing Filtration Cartridge Applications
The polyethersulfone (PES) membrane of the PROPOR HC sterilizing filter cartridges has a pre-filtration membrane in its configuration that prevents premature blockage of the filter when used for complex applications with difficult-to-filter or viscous fluids in the pharmaceutical industry. This results in economical processing thanks to optimized performance.
